Download e-book for kindle: Airways Smooth Muscle: Peptide Receptors, Ion Channels and by Douglas W. P. Hay (auth.), Dr. David Raeburn, Dr. Mark A.

By Douglas W. P. Hay (auth.), Dr. David Raeburn, Dr. Mark A. Giembycz (eds.)

ISBN-10: 303487362X

ISBN-13: 9783034873628

ISBN-10: 3034873646

ISBN-13: 9783034873642

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Additional info for Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction

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J. Cardiovasc. Pharmacol. 1993; 22 (Suppl. 8): S117-20. 129. Power RF, Wharton J, Zhao Y, Bloom SR, Polak JM. Autoradiographic localization of endothelin-l binding sites in the cardiovascular and respiratory systems. J. Cardiovas. Pharmacol. 1989; 13 (Suppl. 5): S50-6. 130. Turner NC, Power RF, Polak JM, Bloom SR, Dollery CT. Endothelin-induced contractions of tracheal smooth muscle and identification of specific endothelin binding sites in the trachea of the rat. Br. J. Pharmacol. 1989; 98: 361-6.

Can be addressed satisfactorily. Thus, considerable work, in particular using human isolated tissues, and in the clinical setting with ET receptor antagonists and/or EeE inhibitors remains before a definitive link can be established between the ETs and the pathophysiology of asthma. 3. Pulmonary Hypertension Pulmonary hypertension is a progressively deteriorating condition characterized by an increase in vascular tone and vasoreactivity and enhanced proliferation of smooth muscle cells, resulting in a significant elevation in pulmonary vascular resistance, which leads to right-heart failure and death.

Cardiovasc. Pharmacol. 1989; 13 (Suppl. 5): S5-S7. 32. Opgenorth TJ, Wu-Wong JR, Shiosaki K. Endothelin-converting enzymes. FASEB J. 1992; 6: 2653-9. 33. Takaoka M, Shiragami K, Fujino K, Miki K, Miyake Y, Yasuda M et at. Phosphoramidon-sensitive endothelin converting enzyme in rat lung. Biochem. Internat. 1991; 25: 697-704. 34. Sawamura, T, Shinmi 0, Kishi N, Sugita Y, Yanagisawa M, Goto K el ai. Characterization of phosphoramidon-sensitive metalloproteinases with endothelin-converting enzyme activity in porcine lung membrane.

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Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction by Douglas W. P. Hay (auth.), Dr. David Raeburn, Dr. Mark A. Giembycz (eds.)


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