By Prof. Dr. Vladimir Veniaminovich Frolkis (auth.)
There is an Inca incantation which said acknowledged approximately: "Lord, provide me non secular peace in order that i will be able to acquiesce to what i will not switch, provide me braveness in order that i will swap what i will swap, and provides me knowledge in order that i will be able to distinguish one from the opposite. " evidently, this incantation may be frequently repeated through any gerontologist, because it is particularly tough to differentiate getting older from the tactics which counterpoint the organism's viability, getting older from ailments, and the mechanisms of getting older in a number of species of animals. in response to N. surprise, who compiled a important bibliography of the works on getting older, greater than 43,000 works on gerontology were released within the final decade. Why can we proceed to disagree with each other and carry that crucial mechanisms are nonetheless principally unknown to us even with that movement of knowledge and a big variety of evidence? what's it that we don't recognize? may possibly it's that we don't comprehend the only sacramental truth which could clarify every little thing, resembling the hormone of getting older, the programmed triggering of a suicide gene, the looks of a unique poisonous agent within the axoplasmic circulation of gear, etc? Goethe as soon as wrote scientist almost always holds convinced components, yet regrettably he lacks their sacred link.
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Additional info for Aging and Life-Prolonging Processes
E. the organism develops from the complex to the simple, from the new, the perfect to the phylogenetic ally more ancient, to a more rudimentary form. Ontogeny is divided into two parts: development and its reflected image, i. e. regressive development, involution, aging. Spenser's philosophical views and Jackson's neurological conception played a certain part in the formation of these concepts. Indeed, many pedect, phylogenetic ally late mechanisms suffer in the aging process. It is enough to recall the substantial shifts in mentality, i.
As the age changes grow, the organism is eliminated from the population. There is another possibility, which is quite real and which has been proved on the basis of much factual material. It presupposes a change in the correlation between the activities of various genes in aging. These shifts in genomic Aging and Evolution 27 regulation may cause a change in the state of the cell membrane: a diminution of the number of receptors and ionic canals, the weakening of the mechanism of the active transport of substances, and the abatement of the synthesis of a special hyperpolarizing factor.
12A, B, C, D). The extent and sequence of the structural changes in various parts of the brain do not fit into the involutional scheme, according to which age disturbances occur first of all in the phylogenetic ally late formations of the brain. An important fact is that great structural changes in neurons are observed in higher and lower animals with different life spans. This confirms their direct link with the chief mechanisms of aging. Metabolic shifts are the basis of the change in the structure and functions of the brain during aging.
Aging and Life-Prolonging Processes by Prof. Dr. Vladimir Veniaminovich Frolkis (auth.)