By James C. Bobrow, MD
This part underwent significant revision for the 2008-2009 version. part eleven stories the anatomy, body structure, embryology, and pathology of the lens. It additionally covers the epidemiology of cataracts and their overview and administration in adults. additionally, an summary of lens and cataract surgical procedure is supplied, problems of cataract surgical procedure are mentioned, and cataract surgical procedure in certain occasions is explored. includes many new photos.
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Extra info for 2008-2009 Basic and Clinical Science Course: Section 11: Lens and Cataract (Basic and Clinical Science Course 2008-2009)
Lens Vesicle As the lens pit continues to invaginate, the stalk of cells that connects it to the surface ectoderm degenerates by programmed cell death (apoptosis), thereby separating the lens cells from the surface ectoderm. The resultant sphere, a single layer of cuboidal cells encased in a basement membrane (the lens capsule), is called the lens vesicle. 2 mm in diameter. Because the lens vesicle was formed through a process of invagination of the surface ectoderm, the apices of the single layer of cells are oriented toward the lumen of the lens vesicle, with the base of each cell attached to the capsule around the periphery of the vesicle.
Jaffe NS, Horwitz J. Evolution and molecular biology oflens proteins. In: Podos SM, Yanoff M, eds. Textbook of Ophthalmology, lishing; 1992. vol 3, Lens and Cataract. New York: Gower Medical Pub- 17 CHAPTER 3 Physiology Throughout life, lens epithelial cells at the equator continue to divide and develop into lens fibers, resulting in continual growth of the lens. The lens cells with the highest metabolic rate are in the epithelium and the outer cortex. These superficial cells ut ilize oxygen and glucose for the active transport of electrolytes, carbohydrates, and amino acids into the lens.
See text for detailed description of artwork. (continued) gestation, the lumen of the lens vesicle is obliterated. The elongated cells are called the primary lells fibers. As the fiber cells mature, their nuclei and other membrane-bound organelles undergo degradation, a process that reduces light scattering. The primary lens fibers make up the embryonic nucleus that will ultimately occupy the central area of the lens in adult life. The cells of the anterior lens vesicle remain as a monolayer of cuboidal cells, the lells epithelium.
2008-2009 Basic and Clinical Science Course: Section 11: Lens and Cataract (Basic and Clinical Science Course 2008-2009) by James C. Bobrow, MD